PEP (Post-Exposure Prophylaxis)

PEP, short for post-exposure prophylaxis, is emergency medicine taken after a possible exposure to HIV, such as condomless sex, a broken condom, sexual assault, or a needle injury. According to the CDC, PEP must be started within 72 hours of the exposure and is taken daily for 28 days. Sooner is better, since effectiveness drops the longer treatment is delayed. It is meant for emergencies, not regular use. PEP is available through emergency rooms, urgent care, sexual health clinics, and many primary care providers. It differs from PrEP (pre-exposure prophylaxis), which is taken on an ongoing basis before any exposure to lower the chance of getting HIV.